DNA Microarrays: Gene Expression Applications

Medical
DNA Microarrays: Gene Expression Applications PDF Author: B.R. Jordan
Publisher: Springer Science & Business Media
ISBN: 3642565174
Category : Medical
Languages : en
Pages : 140

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Book Description
This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book.

DNA Microarrays: Gene Expression Applications

DNA Microarrays: Gene Expression Applications PDF Author: B.R. Jordan
Publisher: Springer Science & Business Media
ISBN: 3642565174
Category : Medical
Languages : en
Pages : 140

View

Book Description
This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book.

Gene Expression Profiling by Microarrays

Gene Expression Profiling by Microarrays PDF Author: Wolf-Karsten Hofmann
Publisher: Cambridge University Press
ISBN: 1139456911
Category : Medical
Languages : en
Pages :

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Book Description
Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.

DNA Microarrays and Gene Expression

DNA Microarrays and Gene Expression PDF Author: Pierre Baldi
Publisher: Cambridge University Press
ISBN: 9781139437608
Category : Science
Languages : en
Pages :

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Book Description
Massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA arrays are in the process of revolutionizing biology and medicine. Using the mRNA of a given cell, at a given time, under a given set of conditions, DNA microarrays can provide a snapshot of the level of expression of all the genes in the cell. Such snapshots can be used to study fundamental biological phenomena such as development or evolution, to determine the function of new genes, to infer the role individual genes or groups of genes may play in diseases, and to monitor the effect of drugs and other compounds on gene expression. Originally published in 2002, this inter-disciplinary introduction to DNA arrays will be of value to anyone with an a interest in this powerful technology.

Gene Expression Profiling with Survival Analysis on Microarray Data

Gene Expression Profiling with Survival Analysis on Microarray Data PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Microarray Gene Expression Data Analysis

Microarray Gene Expression Data Analysis PDF Author: Helen Causton
Publisher: John Wiley & Sons
ISBN: 1444311565
Category : Science
Languages : en
Pages : 176

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Book Description
This guide covers aspects of designing microarray experiments and analysing the data generated, including information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised and wherever possible, the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression. Microarrays are an automated way of carrying out thousands of experiments at once, and allows scientists to obtain huge amounts of information very quickly Short, concise text on this difficult topic area Clear illustrations throughout Written by well-known teachers in the subject Provides insight into how to analyse the data produced from microarrays

Microarrays and Transcription Networks

Microarrays and Transcription Networks PDF Author: M. Francis Shannon
Publisher: CRC Press
ISBN: 1498713734
Category : Science
Languages : en
Pages : 130

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Book Description
While every cell of an organism has an identical genomic content, extremely complex networks exist to tailor the genomic output to the needs of that cell. This program of gene expression is different for every cell type and stage of development. In addition, the cell can respond to its environment by modulating its gene expression program in a fair

Advanced Analysis Of Gene Expression Microarray Data

Advanced Analysis Of Gene Expression Microarray Data PDF Author: Aidong Zhang
Publisher: World Scientific Publishing Company
ISBN: 9813106646
Category : Science
Languages : en
Pages : 356

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Book Description
This book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data.Biomedical researchers will find this book invaluable for learning the cutting-edge methods for analyzing gene expression microarray data. Specifically, the coverage includes the following state-of-the-art methods:• Gene-based analysis: the latest novel clustering algorithms to identify co-expressed genes and coherent patterns in gene expression microarray data sets• Sample-based analysis: supervised and unsupervised methods for the reduction of the gene dimensionality to select significant genes. A series of approaches to disease classification and discovery are also described• Pattern-based analysis: methods for ascertaining the relationship between (subsets of) genes and (subsets of) samples. Various novel pattern-based clustering algorithms to find the coherent patterns embedded in the sub-attribute spaces are discussed• Visualization tools: various methods for gene expression data visualization. The visualization process is intended to transform the gene expression data set from high-dimensional space into a more easily understood two- or three-dimensional space.

Association Rule Mining for Gene Expression Profiling of DNA Microarray Data

Association Rule Mining for Gene Expression Profiling of DNA Microarray Data PDF Author: Xiang-Rong Jiang
Publisher:
ISBN:
Category : DNA microarrays
Languages : en
Pages : 254

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Prospects for DNA Microarray-based Gene Expression Profiling in Diagnostics

Prospects for DNA Microarray-based Gene Expression Profiling in Diagnostics PDF Author: Malorye Branca
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Microarray Analysis

Microarray Analysis PDF Author: Mark Schena
Publisher: Wiley-Liss
ISBN: 9780471414438
Category : Science
Languages : en
Pages : 664

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Book Description
This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverageincludes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies.